I don't know about Isky cams, but I used a Reed cam in my 401. Great cam and no problems! They do custom grinds and all their cores are American made. I just talked to them about a 6 cylinder cam for my 4.0 stroker that I am going to build. The price is a little higher, but I am willing to pay a little more for American made quality. They said that they haven't had any problems with their cams flattening out, and that some of the other bigger name cam manufacturers are using China cores. Check out thier web site www.reedcams.com Great people to work with also.